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The Unreasonable Redundancy of Nature’s Protein Folds

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🚀 Discover this awesome post from Hacker News 📖 📂 **Category**: 📌 **What You’ll Learn**: Arda Goreci · May 20, 2026 Over the last few years, deep neural networks have made generative language modeling dramatically more powerful, giving us large language models. A similar leap happened for continuous modalities like images and videos. Recently, similar techniques have been applied to the generative modeling of biomolecules with great success. Models such as DeepMind's AlphaFold3 made it much easier to predict biomolecular interactions, including drug-protein and antibody-protein complexes, and soon after people figured out how to re-purpose these capabilities to design drug-like…

The American Missile Crisis | Contrary Research

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💥 Check out this insightful post from Hacker News 📖 📂 **Category**: 📌 **What You’ll Learn**: Recent global conflicts, from Russia and Ukraine to Iran and Israel, have seen a resurgent awareness of the frailty of US munitions stock, which has been drawn down by both direct and indirect involvement in these events. While exact stockpile volumes are not disclosed, it is estimated that supplies of US warheads and the missiles that carry them have declined by nearly an order of magnitude since their peak during the Cuban Missile Crisis. Analysts have estimated that in the event of a conflict…

The Ultimate Disassembly Framework – Capstone – The Ultimate Disassembler

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🚀 Explore this must-read post from Hacker News 📖 📂 **Category**: 💡 **What You’ll Learn**: Welcome Capstone is a lightweight multi-platform, multi-architecture disassembly framework. Our target is to make Capstone the ultimate disassembly engine for binary analysis and reversing in the security community. Highlight features Multi-architectures: ARM, ARM64 (ARMv8), BPF, Ethereum VM, M68K, M680X, Mips, MOS65XX, PowerPC, RISC-V, SH, Sparc, SystemZ, TMS320C64X, TriCore, Webassembly, XCore and X86 (16, 32, 64). Clean/simple/lightweight/intuitive architecture-neutral API. Provide details on disassembled instruction (called “decomposer” by some others). Provide some semantics of the disassembled instruction, such as list of implicit registers read & written. Implemented…

I Don’t Want My Search Engine to Think for Me — SearchZee Blog

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🚀 Discover this awesome post from Hacker News 📖 📂 **Category**: 📌 **What You’ll Learn**: June 2, 2026 · 6 min read AI search summaries feel like progress. They aren't. Here's the case for search that returns results and nothing else. The shift happened gradually and then all at once. One day you searched for something, got a page of blue links, clicked through, read the thing. The next day there was a box at the top — confident, authoritative, already summarized — and the links felt almost redundant. Google calls it AI Overviews. Bing calls it Copilot answers. Perplexity…

Mental health: although screens can play a negative role, more than 6 out of 10 people turn to artificial intelligence for psychological support.

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💥 Check out this awesome post from Hacker News 📖 📂 **Category**: 📌 **What You’ll Learn**: AXA is today releasing its latest edition of Mind Health1 report, a global study carried out in partnership with IPSOS. This latest edition highlights the continuous deterioration of people’s psychological state, the rise in the use of artificial intelligence to talk about their mental health, and the responsibility of companies to support individuals.Mental health worldwide continues to deteriorate: in 10 of the 16 countries in the study, mental health scores are at their lowest since the first survey wave in 2021. 46% of those surveyed say they…

c0deJedi/nbd-vram: Use your NVIDIA GPU’s VRAM as swap space on Linux. Built for laptops with soldered memory and no upgrade path. If you have an RTX card sitting there with 8GB of VRAM and you’re getting swapped to SSD, this puts that VRAM to work · GitHub

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🚀 Read this awesome post from Hacker News 📖 📂 **Category**: ✅ **What You’ll Learn**: Use your NVIDIA GPU's VRAM as swap space on Linux. Built for laptops with soldered memory and no upgrade path. If you have an RTX card sitting there with 8GB of VRAM and you're getting swapped to SSD, this puts that VRAM to work. Tested on: RTX 3070 Laptop (GA104M, 16 GB physical, 8 GB VRAM), driver 580.159.03, kernel 6.17, Pop!_OS. Allocated 7 GB for swap. End result including zram and SSD swap ~46 GB, tripled the addressable memory. Overflow order is: RAM fills, then…

Single file Gleam BEAM programs with escript

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🚀 Explore this awesome post from Hacker News 📖 📂 **Category**: ✅ **What You’ll Learn**: Gleam is a type safe and scalable language for the Erlang virtual machine and JavaScript runtimes. Today Gleam v1.17.0 has been published. Gleam Gathering But first: the first videos from the first ever all-Gleam conference have been released! You can view them on the Gleam Gathering YouTube account. The event was a roaring success and loads of fun. Stay tuned for news of the next one in 2027! Right, back to the release coverage. BEAM escripts When running on the Erlang virtual machine Gleam code…

My thoughts after using Clojure for about a month

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🔥 Check out this trending post from Hacker News 📖 📂 **Category**: ✅ **What You’ll Learn**: I am now generating this website with Clojure (yes, right after rewriting it in GNU Make and shell; I have a problem, ok?). In a personal tradition, I used writing a static site generator as the project to play with and learn Clojure as a new language. While I’ve long scoffed at Clojure for its copious syntax (three types of brackets!?), it turns out to be pretty ergonomic and powerful. Here are my impressions after playing around with Clojure for about a month. More…

CT Scans of the EV You Can’t Buy in America

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✨ Explore this trending post from Hacker News 📖 📂 **Category**: 💡 **What You’ll Learn**: Design to RealityEvolution of the Plastic BottleIn the dark nights of my soul, I fret about how inconsistently engineered my life is. The coffee table I made a year or two ago was intended to look like the dining room table I built a few years earlier, but in reality the two bear only a vague resemblance to each other. Open a drawer of my tool chest at random, and perhaps you’ll find a thematically-aligned collection of well-loved hand tools, meticulously cut into a nest…

The advertising cartel coming to your web browser

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🔥 Explore this trending post from Hacker News 📖 📂 **Category**: 📌 **What You’ll Learn**: When Meta, Google and Apple agree on a “privacy” feature, watch out. The three companies (along with Mozilla, which is on one of their “ad features in the browser” kicks again) are drawing up a built-in advertising measurement system, called Attribution Level 1, as a standard feature of web browsers. The system is intended to measure the effectiveness of advertising by enabling advertisers to correlate “impressions,” the occasions on which someone saw an ad, with “conversions,” when people bought something. Don’t look for a section…